Overall (n = 74) | Younger group (n = 42) | Elderly group (n = 32) | p value | ||
Chemotherapy | Adjuvant | 44 | 31 | 13 | 0.0094 |
Recurrence | 25 | 10 | 15 | ||
Intensive, Induction | 5 | 1 | 4 | ||
Regimen | GEM + CBDCA | 44 | 27 | 17 | 0.3333 |
PTX + CBDCA | 30 | 15 | 15 | ||
Planned cycles | 1/2/3/4/5/6 cycles | 3/33/8/23/0/7 | 3/19/5/13/0/2 | 0/14/3/10/0/5 | 0.3230 |
Received cycles | 1/2/3/4/5/6 cycles | 4/33/9/21/1/6 | 3/19/6/12/0/2 | 1/14/3/9/1/4 | 0.6133 |
Compliance | Completed | 71(95.9%) | 41(97.6%) | 30(93.8%) | 0.2304 |
Discontinued | 2(2.7%) | 0(2.4%) | 2*(6.3%) | ||
Dose reduction | 8(10.8%) | 5(11.9%) | 3(9.4%) | ||
Delayed | 3(4.1%) | 3(7.1%) | 0(0.0%) | ||
Response to treatment (RECIST) | Partial response (PR) | 11 | 2 | 9 | 0.1100 |
(n = 30) | Stable disease (SD) | 19 | 9 | 10 | |
Toxicities | ≥Grade 3/4 | 43(58.1%) | 23(54.8%) | 20(62.5%) | 0.5040 |